These are not your mother's bath salts. In fact, they aren't bath salts at all, judging by the ingredients. The fact that they're marketed as such doesn't mean much; they're also marketed as experimental plant food.
Sold legally in convenience stores and on the Internet, "the powders often contain: mephedrone and methylenedioxypyrovalerone, also known as MDPV."[1] Smoked, injected, and/or snorted, these chemicals offer two different highs. And similar, incredibly serious, side effects.
Documented information is a little difficult to come by, but we'll see what we can dig up.
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Chemistry
Methylenedioxypyrovalerone (MDPV)
Despite headlines calling MDPV 'synthetic cocaine,' it is an analog[2] of pyrovalerone - a drug developed in the late 1960s to treat chronic fatigue and as an appetite suppressant. According to the DEA Office of Diversion Control, "MDPV
is structurally related to cathinone, an active alkaloid found in the khat plant."
With a chemical structure more like MDMA (Ecstasy) than cocaine, it reportedly acts in a manner similar to Ritalin or Concerta (methylphenidate), and Wellbutrin (buproprion) - only much, much stronger. The high is more like that from cocaine - more 'selfish,' less 'social' - which may account for the comparison.
Mephedrone
From what I've read, mephedrone is also derived from (or chemically similar to)[3] cathinone compounds found in Catha edulis (khat), a flowering plant of East Africa and the Arabian Peninsula. First synthesized in the late 1920s, mephedrone was virtually unknown until its rediscovery in 2003. By 2007, it was available on the Internet; in 2008, Israel was the first country to make it illegal. (The EU ruled it illegal across Europe in December, 2010.)
Belonging to the amphetamine and cathinone drug classes, mephedrone is reported to have a high more like MDMA (Ecstasy) (I love everyone!) than cocaine (Everyone should love me!). However, users also report a strong desire to take more before they completely come down, which seems more like the reports on cocaine.
Side Effects
Neither drug has been extensively studied, so the accounts of side effects are mostly from users.
Methylenedioxypyrovalerone (MDPV)
Once again, from the DEA Office of Diversion Control:
The acute side effects of MDPV include tachycardia, hypertension, vasoconstriction, and sweating. The duration of the subjective effects is about 3 to 4 hours and the side effects continuing a total of 6 to 8 hours after administration. Higher doses of MDPV have caused intense, prolonged panic attacks in stimulant-intolerant users. Users have reported bouts of psychosis induced by sleep deprivation and becoming addicted after using higher doses or using at more frequent dosing intervals.
Mephedrone
Medical News Today reports:
According to a survey by Mixmag, a dancing and clubbing magazine:
- 67% of users experienced hyperhidrosis (excessive sweating)
- 51% of users experienced headaches
- 43% of users experienced heart palpitations
- 27% of users experienced nausea
- 15% of users had blue or cold fingers
Non-survey (anecdotal) reports indicate mephedrone may have the following effects on some users:
- Severe panic attacks
- Hallucinations
- Paranoia
The comments section of this article adds more rather frightening, first-hand stories of mephedrone side effects and withdrawal.
Given the similarities between these two drugs, one can only imagine the potential dangers of combining them.
United States
Neither MDPV nor mephedrone are approved for medical use in the United States. Official information on users of either drug in the United States is virtually non-existent.
Sources
Officials know, based on Internet company locations, that some of these 'bath salts' are entering the United States from Europe. In an article about mephedrone last year, Guardian News and Media, quoting Druglink magazine, noted that "[d]ealers in Britain are spending £2,500 to ship one kilogram from China, then sell it at £10 a gram for a profit of £7,500." (This was before EU laws changed.)
A quick search shows that mephedrone 'research chemicals' can be purchased online from sources in Latvia, Cameroon, the US, the UK, and Malaysia. MDPV can be ordered from the same companies, as well as ones in China, Hungary, Germany, and Spain.
Illicit Distribution
While not yet illegal in the United States, state and local law enforcement in several states report encounters with MDPV. There were 75 reports from January to September, 2010; 2 in 2009. Information from the DEA on mephedrone simply mentions Internet sales and promotions.
Twenty-five states report interaction with individuals who have used 'bath salts.' Louisiana leads the nation, with almost 50% of all encounters. As a result, they have outlawed these products, rapidly reducing calls and sending shoppers across state lines. A northern Mississippi county responded to 30 calls in only two months, possibly due to an increase in cross-state traffic.
More than one state is considering following Louisiana's lead and enacting bans.
Control Status
Because they aren't marketed for human consumption, neither mephedrone nor MDPV appear on a U.S. drug schedule. However, as they are considered analog(ue)s of Schedule I drugs, a provision of the Controlled Substance Act (Title 21 United States Code 813) would allow prosecution of cases involving one or both of the substances.
Outlook
People are dying from shooting, sniffing, and smoking this stuff. Manufacturers and sellers get around laws in the United States by labeling their products "not for human consumption," though there's little doubt in anyone's mind the precise intent of these items. It can take years for the federal government to review, regulate, and get these substances off the market.
And, honestly, pulling 'bath salts' will probably do nothing more than make room for the next designer drugs.
- AZCentral.com: Officials Fear Bath Salts are Growing Drug Problem
- ChemiCool.com: "An analog is a drug whose structure is related to that of another drug but whose chemical and biological properties may be quite different." (Ed. note: Frequently, the term is used to describe, right or wrong, an artificial derivative of a specific drug or chemical.)
- a.) Wikipedia: "Mephedrone ... is chemically similar to the cathinone compounds found in the khat plant of eastern Africa."
b.) Medical News Today: "Mephedrone is a synthetic (artificial) substance based on the (cathinone) compounds that exist in the Khat plant of East Africa."